The CAB Genomics Group focuses incorporate state-of-art analytic approaches to understand how the tumorigenesis and relevant biological processes shaped by genomic variations. The team is also of interests in establishing genomics analytic pipelines to support the work of St. Jude investigators.
We mainly focus on these areas:
The CAB Genomics Group is primarily a bioinformatic group that uses a wide range of genomic, bioinformatic, and statistical methods including:
If you are interested in joining please go to the recruitment page.
New papers! Dickerson et al. 2022; BloodCancerDiscovery;Zhao et al. 2022; JNCI;Drosos et al. 2022; MolecularCell;Graca et al. 2022; NatCommun; Kudo to Wojciech, co-first author Qi et al. 2022; JPathol;
New paper! Wang et al. 2021 published in Life Sci. Alliance: PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. Kudo to Wojciech, first co-first author with St. Jude PIs
New paper! Xu et al. 2021 published in Genome Bio.: Acute depletion of CTCF rewires genome-wide chromatin accessibility. Press Release
New paper! Montefiori et al. 2021 published in Cancer Discov.: Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage Ambiguous Stem Cell Leukemia
New paper! Zong et al. 2021 published in J. Exp. Med.: Foxp3 Enhancers Synergize to Maximize Regulatory T Cell Suppressive Capacity