The CAB Genetics Group focuses on the association of inherited or acquired genetic variations with clinical or phenotypic traits in humans. We are also interested in establishing new bioinformatic and statistical pipelines to enhance researching practices of St. Jude investigators.
We mainly focus on these areas:
The CAB Genetics Group is primarily a statistical genetics/bioinformatic group that uses a wide range of genomic, bioinformatic, and statistical methods including:
If you are interested in joining please go to the recruitment page.
New papers! Dickerson et al. 2022; BloodCancerDiscovery;Zhao et al. 2022; JNCI;Drosos et al. 2022; MolecularCell;Graca et al. 2022; NatCommun; Kudo to Wojciech, co-first author Qi et al. 2022; JPathol;
New paper! Wang et al. 2021 published in Life Sci. Alliance: PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. Kudo to Wojciech, first co-first author with St. Jude PIs
New paper! Xu et al. 2021 published in Genome Bio.: Acute depletion of CTCF rewires genome-wide chromatin accessibility. Press Release
New paper! Montefiori et al. 2021 published in Cancer Discov.: Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage Ambiguous Stem Cell Leukemia
New paper! Zong et al. 2021 published in J. Exp. Med.: Foxp3 Enhancers Synergize to Maximize Regulatory T Cell Suppressive Capacity