Welcome to CAB at St. Jude

SJCRH Center for Applied Bioinformatics (CAB) is an institutional shared resource, with the mission to provide state-of-the-art bioinformatics services to St. Jude investigators. We maintain the highest level of scientific rigor by carefully vetting and documenting all bioinformatics methods and pipelines. All methods are shared with the international biomedical research community.

At the CAB, we believe that “Discovery Leads to Cure”, which is what we are striving for. We also advocate an open science culture and help cultivate a highly collaborative environment for scientific research.

Joining St. Jude

If you are interested in joining please go to the recruitment page.


We are grateful for funding from the National Cancer Institute at National Institute of Health


Oct 19th 2021

New paper! Wang et al. 2021 published in Life Sci. Alliance: PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands. Kudo to Wojciech, first co-first author with St. Jude PIs

Aug 24th 2021

New paper! Xu et al. 2021 published in Genome Bio.: Acute depletion of CTCF rewires genome-wide chromatin accessibility. Press Release

Jun 8th 2021

New paper! Montefiori et al. 2021 published in Cancer Discov.: Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage Ambiguous Stem Cell Leukemia

Jun 4th 2021

New paper! Zong et al. 2021 published in J. Exp. Med.: Foxp3 Enhancers Synergize to Maximize Regulatory T Cell Suppressive Capacity

Apr 5th 2021

New paper! Chen et al. 2021 published in Nat Genet, Dr. Mohamed Nadhir Djekidel(co-first) deciphers the Mysterious Roles of PRC Complexes in Histone Modification

... see all News