Publications

2022:5

1. Nature

   Broadly neutralizing antibodies target a haemagglutinin anchor epitope

   Guthmiller Jenna J, Han Julianna, Utset Henry A, Li Lei, Lan Linda Yu-Ling, Henry Carole, Stamper Christopher T, McMahon Meagan, O’Dell George, Fernández-Quintero Monica L, others

   Nature 2022
2. Briefings in Bioinfo

   Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens

   Li Lei, Changrob Siriruk, Fu Yanbin, Stovicek Olivia, Guthmiller Jenna J, McGrath Joshua JC, Dugan Haley L, Stamper Christopher T, Zheng Nai-Ying, Huang Min, others

   Briefings in Bioinformatics 2022
3. Trends in Immunology

   Memory B cell diversity: insights for optimized vaccine design

   McGrath Joshua JC, Li Lei, Wilson Patrick C

   Trends in Immunology 2022
4. Frontiers in Genetic

   Selecting Representative Samples From Complex Biological Datasets Using K-Medoids Clustering

   Li Lei, Lan Linda Yu-Ling, Huang Lei, Ye Congting, Andrade Jorge, Wilson Patrick C

   Frontiers in Genetics 2022
5. The Journal of Immun

   B cell convergence to distinct broadly reactive epitopes revealed by chimeric hemagglutinin vaccination

   Guthmiller Jenna, Li Lei, Lan Linda Yu-Ling, Henry Carole, Stamper Christopher, Freyn Alec, Utset Henry, Han Julianna, Palese Peter, Coughlan Lynda, others

   The Journal of Immunology 2022

2021:9

1. MBio

   SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

   Guthmiller Jenna J, Stovicek Olivia, Wang Jiaolong, Changrob Siriruk, Li Lei, Halfmann Peter, Zheng Nai-Ying, Utset Henry, Stamper Christopher T, Dugan Haley L, others

   MBio 2021
2. PLoS pathogens

   Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity

   Surette Fionna A, Guthmiller Jenna J, Li Lei, Sturtz Alexandria J, Vijay Rahul, Pope Rosemary L, McClellan Brandon L, Pack Angela D, Zander Ryan A, Shao Peng, others

   PLoS pathogens 2021
3. Mbio

   An egg-derived sulfated N-Acetyllactosamine glycan is an antigenic decoy of influenza virus vaccines

   Guthmiller Jenna J, Utset Henry A, Henry Carole, Li Lei, Zheng Nai-Ying, Sun Weina, Costa Vieira Marcos, Zost Seth, Huang Min, Hensley Scott E, others

   Mbio 2021
4. Journal of Experimen

   Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation

   Vijay Rahul, Guthmiller Jenna J, Sturtz Alexandria J, Crooks Sequoia, Johnson Jordan T, Li Lei, Lan Linda Yu-Ling, Pope Rosemary L, Chen Yani, Rogers Kai J, others

   Journal of Experimental Medicine 2021
5. Immunity

   Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets

   Dugan Haley L, Stamper Christopher T, Li Lei, Changrob Siriruk, Asby Nicholas W, Halfmann Peter J, Zheng Nai-Ying, Huang Min, Shaw Dustin G, Cobb Mari S, others

   Immunity 2021
6. Avian Diseases

   H7N1 low pathogenicity avian influenza viruses in poultry in the United States during 2018

   Lee Dong-Hun, Killian Mary Lea, Deliberto Thomas J, Wan Xiu-Feng, Lei Li, Swayne David E, Torchetti Mia Kim

   Avian Diseases 2021
7. Science Translationa

   First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes

   Guthmiller Jenna J, Han Julianna, Li Lei, Freyn Alec W, Liu Sean TH, Stovicek Olivia, Stamper Christopher T, Dugan Haley L, Tepora Micah E, Utset Henry A, others

   Science Translational Medicine 2021
8. Cell reports methods

   Improved integration of single-cell transcriptome and surface protein expression by LinQ-View

   Li Lei, Dugan Haley L, Stamper Christopher T, Lan Linda Yu-Ling, Asby Nicholas W, Knight Matthew, Stovicek Olivia, Zheng Nai-Ying, Madariaga Maria Lucia, Shanmugarajah Kumaran, others

   Cell reports methods 2021
9. MBio

   Cross-neutralization of emerging SARS-CoV-2 variants of concern by antibodies targeting distinct epitopes on spike

   Changrob Siriruk, Fu Yanbin, Guthmiller Jenna J, Halfmann Peter J, Li Lei, Stamper Christopher T, Dugan Haley L, Accola Molly, Rehrauer William, Zheng Nai-Ying, others

   MBio 2021

2020:7

1. BMC bioinformatics

   Multi-task learning sparse group lasso: a method for quantifying antigenicity of influenza A (H1N1) virus using mutations and variations in glycosylation of Hemagglutinin

   Li Lei, Chang Deborah, Han Lei, Zhang Xiaojian, Zaia Joseph, Wan Xiu-Feng

   BMC bioinformatics 2020
2. Elife

   HA stabilization promotes replication and transmission of swine H1N1 gamma influenza viruses in ferrets

   Hu Meng, Yang Guohua, DeBeauchamp Jennifer, Crumpton Jeri Carol, Kim Hyunsuh, Li Lei, Wan Xiu-Feng, Kercher Lisa, Bowman Andrew S, Webster Robert G, others

   Elife 2020
3. Immunological review

   Imprinting, immunodominance, and other impediments to generating broad influenza immunity

   Knight Matthew, Changrob Siriruk, Li Lei, Wilson Patrick C

   Immunological reviews 2020
4. Journal of Virology

   Tissue tropisms of avian influenza A viruses affect their spillovers from wild birds to pigs

   Zhang Xiaojian, Cunningham Fred L, Li Lei, Hanson-Dorr Katie, Liu Liyuan, Waters Kaitlyn, Guan Minhui, Olivier Alicia K, Schmit Brandon S, Nolting Jacqueline M, others

   Journal of Virology 2020
5. Immunity

   Polyreactive broadly neutralizing B cells are selected to provide defense against pandemic threat influenza viruses

   Guthmiller Jenna J, Lan Linda Yu-Ling, Fernández-Quintero Monica L, Han Julianna, Utset Henry A, Bitar Dalia J, Hamel Natalie J, Stovicek Olivia, Li Lei, Tepora Micah, others

   Immunity 2020
6. The Journal of Immun

   Understanding memory B cell responses to a chimeric-based universal influenza virus vaccine candidate

   Lan Linda, Li Lei, Huang Min, Henry Carole, Zheng Nai-Ying, Chen Yao-Qing, McNair Mahalia, Meade Philip, Guthmiller Jenna, Dugan Haley, others

   The Journal of Immunology 2020
7. Journal

   SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike (preprint)

   Guthmiller Jenna J, Stovicek Olivia, Wang Jiaolong, Changrob Siriruk, Li Lei, Halfmann Peter, Zheng Nai-Ying, Utset Henry, Stamper Christopher T, Dugan Haley L, others

   2020

2019:3

1. Bioinformatics

   Graph-guided multi-task sparse learning model: a method for identifying antigenic variants of influenza A (H3N2) virus

   Han Lei, Li Lei, Wen Feng, Zhong Lei, Zhang Tong, Wan Xiu-Feng

   Bioinformatics 2019
2. Journal of Virology

   Aerosol transmission of gull-origin Iceland subtype H10N7 influenza A virus in ferrets

   Guan Minhui, Hall Jeffrey S, Zhang Xiaojian, Dusek Robert J, Olivier Alicia K, Liu Liyuan, Li Lei, Krauss Scott, Danner Angela, Li Tao, others

   Journal of Virology 2019
3. Cell host & microbe

   Emerging from the shadow of hemagglutinin: neuraminidase is an important target for influenza vaccination

   Krammer Florian, Li Lei, Wilson Patrick C

   Cell host & microbe 2019

2018:4

1. Clinical Infectious

   Imprinting of repeated influenza A/H3 exposures on antibody quantity and antibody quality: implications for seasonal vaccine strain selection and vaccine performance

   Kosikova Martina, Li Lei, Radvak Peter, Ye Zhiping, Wan Xiu-Feng, Xie Hang

   Clinical Infectious Diseases 2018
2. Journal of virology

   Genetic evidence supports sporadic and independent introductions of subtype H5 low-pathogenic avian influenza A viruses from wild birds to domestic poultry in North America

   Li Lei, Bowman Andrew S, DeLiberto Thomas J, Killian Mary L, Krauss Scott, Nolting Jacqueline M, Torchetti Mia Kim, Ramey Andrew M, Reeves Andrew B, Stallknecht David E, others

   Journal of virology 2018
3. Virology

   Evolutionary pathway for the 2017 emergence of a novel highly pathogenic avian influenza A (H7N9) virus among domestic poultry in Tennessee, United States

   Li Lei, DeLiberto Thomas J, Killian Mary L, Torchetti Mia K, Wan Xiu-Feng

   Virology 2018
4. PLoS Pathogens

   Tissue tropisms opt for transmissible reassortants during avian and swine influenza A virus co-infection in swine

   Zhang Xiaojian, Sun Hailiang, Cunningham Fred L, Li Lei, Hanson-Dorr Katie, Hopken Matthew W, Cooley Jim, Long Li-Ping, Baroch John A, Li Tao, others

   PLoS Pathogens 2018

2017:3

1. Journal of Clinical

   Detection of antigenic variants of subtype H3 swine influenza A viruses from clinical samples

   Martin Brigitte E, Bowman Andrew S, Li Lei, Nolting Jacqueline M, Smith David R, Hanson Larry A, Wan Xiu-Feng

   Journal of Clinical Microbiology 2017
2. Clinical Infectious

   Differential effects of prior influenza exposures on H3N2 cross-reactivity of human postvaccination sera

   Xie Hang, Li Lei, Ye Zhiping, Li Xing, Plant Ewan P, Zoueva Olga, Zhao Yangqing, Jing Xianghong, Lin Zhengshi, Kawano Toshiaki, others

   Clinical Infectious Diseases 2017
3. Analyst

   Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets

   Huang Guangzao, Yuan Mingshun, Chen Moliang, Li Lei, You Wenjie, Li Hanjie, Cai James J, Ji Guoli

   Analyst 2017

2016:1

1. BookChapter

   Identification of glycosylation sites and mutations determining antigenic drift events for influenza A viruses using sparse group lasso regression

   Li Lei, Han Lei, Wan Xiu-feng

   In GLYCOBIOLOGY 2016

2015:3

1. BMC plant biology

   PlantOrDB: A genome-wide ortholog database for land plants and green algae

   Li Lei, Ji Guoli, Ye Congting, Shu Changlong, Zhang Jie, Liang Chun

   BMC plant biology 2015
2. Bioinformatics

   PASPA: a web server for mRNA poly (A) site predictions in plants and algae

   Ji Guoli, Li Lei, Li Qingshun Q, Wu Xiangdong, Fu Jingyi, Chen Gong, Wu Xiaohui

   Bioinformatics 2015
3. Scientific reports

   mirPRo–a novel standalone program for differential expression and variation analysis of miRNAs

   Shi Jieming, Dong Min, Li Lei, Liu Lin, Luz-Madrigal Agustin, Tsonis Panagiotis A, Del Rio-Tsonis Katia, Liang Chun

   Scientific reports 2015