Hongjian Jin

Sr. Bioinoformatics Research Scientist
St. Jude Profile
j/hongjian-jin
ORCID
0000-0003-3833-7170
GitHub
stjudecab
Google Scholar
Hongjian Jin
NCBI Bibliography
Hongjian Jin
LinkedIn
Hongjian Jin
Email
hongjian.jinobfuscate#stjude.org

Overview

Dr. Hongjian Jin is a senior bioinformatics research scientist at St. Jude Children’s Research Hospital, He is particularly interested in understanding transcriptional regulation and its roles in childhood and adult cancer.

His expertise includes analyisis, integration and intepretation of epigenetics and transcriptomics data:

  • RNA-Seq, scRNA-Seq
  • ATAC-Seq, scATAC-Seq
  • ChIP-Seq, CUT&RUN CUT&TAG
  • FAIRE-Seq, DNase-Seq
  • Microarry, Methylation Array

Education

  • PhD, Zhejiang University, Hangzhou, China (2007)
  • MS, - Zhejiang University, Hangzhou, China (2002)

Professional Experience

Time Position PI/Supervisor Institution
2019- Sr. Bioinformatics Yiping Fan St. Jude Children’s Research Hospital
  Research Scientist    
2016-2019 Bioinformatics Jinghui Zhang / St. Jude Children’s Research Hospital
  Research Scientist Yiping Fan  
2014-2016 Research Assistant Ramana V Davuluri Northwestern University
  Professor    

Publications

For a full list (GEO|SRA|Browser|Code) see below , or Google Scholar , or Pubmed

Full List

*denotes equal contribution

2021:1

  1. iScience
    17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma
    Singh S., Abu-Zaid A., Lin W., Low J., Abdolvahabi A., Jin H., Wu Q., Cooke B., Fang J., Bowling J., Vaithiyalingam S., Currier D., Yun M. K., Fernando D. M., Maier J., Tillman H., Bulsara P., Lu Z., Das S., Shelat A., Li Z., Young B., Lee R., Rankovic Z., Murphy A. J., White S. W., Davidoff A. M., Chen T., Yang J.
    iScience 2021

2020:3

  1. Nat Immunol
    Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
    Abdelsamed H. A., Zebley C. C., Nguyen H., Rutishauser R. L., Fan Y., Ghoneim H. E., Crawford J. C., Alfei F., Alli S., Ribeiro S. P., Castellaw A. H., McGargill M. A., Jin H., Boi S. K., Speake C., Serti E., Turka L. A., Busch M. E., Stone M., Deeks S. G., Sekaly R. P., Zehn D., James E. A., Nepom G. T., Youngblood B.
    Nat Immunol 2020
  2. Elife
    The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth
    Mondal B., Jin H., Kallappagoudar S., Sedkov Y., Martinez T., Sentmanat M. F., Poet G. J., Li C., Fan Y., Pruett-Miller S. M., Herz H. M.
    Elife 2020
  3. Bioinformatics
    ChIPseqSpikeInFree: a ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in
    Jin H., Kasper L. H., Larson J. D., Wu G., Baker S. J., Zhang J., Fan Y.
    Bioinformatics 2020

2019:4

  1. Acta Neuropathol
    Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
    Silveira A. B., Kasper L. H., Fan Y., Jin H., Wu G., Shaw T. I., Zhu X., Larson J. D., Easton J., Shao Y., Yergeau D. A., Rosencrance C., Boggs K., Rusch M. C., Ding L., Zhang J., Finkelstein D., Noyes R. M., Russell B. L., Xu B., Broniscer A., Wetmore C., Pounds S. B., Ellison D. W., Zhang J., Baker S. J.
    Acta Neuropathol 2019
  2. Acta Neuropathol
    H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
    Silveira A. B., Kasper L. H., Fan Y., Jin H., Wu G., Shaw T. I., Zhu X., Larson J. D., Easton J., Shao Y., Yergeau D. A., Rosencrance C., Boggs K., Rusch M. C., Ding L., Zhang J., Finkelstein D., Noyes R. M., Russell B. L., Xu B., Broniscer A., Wetmore C., Pounds S. B., Ellison D. W., Zhang J., Baker S. J.
    Acta Neuropathol 2019
  3. JCI Insight
    The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response
    Xu Y., Melo-Cardenas J., Zhang Y., Gau I., Wei J., Montauti E., Zhang Y., Gao B., Jin H., Sun Z., Lee S. M., Fang D.
    JCI Insight 2019
  4. Cancer Cell
    Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression
    Larson J. D., Kasper L. H., Paugh B. S., Jin H., Wu G., Kwon C. H., Fan Y., Shaw T. I., Silveira A. B., Qu C., Xu R., Zhu X., Zhang J., Russell H. R., Peters J. L., Finkelstein D., Xu B., Lin T., Tinkle C. L., Patay Z., Onar-Thomas A., Pounds S. B., McKinnon P. J., Ellison D. W., Zhang J., Baker S. J.
    Cancer Cell 2019

2016:1

  1. Oncotarget
    Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer
    Jin H. J., Jung S., DebRoy A. R., Davuluri R. V.
    Oncotarget 2016