Patrick Schreiner

Bioinoformatics Research Scientist
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patrick.schreinerobfuscate#stjude.org

Overview

Patrick’s graduate research was focused on the origin and function of sRNA mainly in the yellow fever mosquito. In addition to mosquito samples, Patrick also has experience in analyzing data from bacteria, yeast, ferret, mice, and human samples. He received his Ph.D. in Genetics, Genomics, and Bioinformatics from the University of California, Riverside in 2017 before coming to St. Jude as a Bioinformatics Research Scientist. Patrick has led the execution of projects that mine and analyze big data from internal and external datasets. His particular research areas of interest include Transcriptomics, Immunology, and Single-Cell Omics.

NGS Data that Patrick knows how to analyze:

  • RNA-Seq
  • scRNA-Seq
  • scATAC-Seq
  • Microarray (Expression)
  • WGBS/TEBS

Education

  • PhD, University of California, Riverside (2017)
  • BS, Loyola University of Chicago (2012)

Professional Experience

Time Position PI/Supervisor Institution
2017- Bioinformatics Gang Wu / St. Jude Children’s Research Hospital
  Research Scientist Yiping Fan  

2021:1

  1. Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail
    Lowe Brandon R, Yadav Rajesh K, Henry Ryan A, Schreiner Patrick, Matsuda Atsushi, Fernandez Alfonso G, Finkelstein David, Campbell Margaret, Kallappagoudar Satish, Jablonowski Carolyn M, others
    Elife 2021

2020:2

  1. Synergism of TNF-αand IFN-γtriggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes
    Karki Rajendra, Sharma Bhesh Raj, Tuladhar Shraddha, Williams Evan Peter, Zalduondo Lillian, Samir Parimal, Zheng Min, Sundaram Balamurugan, Banoth Balaji, Malireddi RK Subbarao, others
    Cell 2020
  2. MyD88/CD40 signaling retains CAR T cells in a less differentiated state
    Prinzing Brooke, Schreiner Patrick, Bell Matthew, Fan Yiping, Krenciute Giedre, Gottschalk Stephen
    JCI insight 2020

2019:1

  1. Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia
    Tian Liqing, Shao Ying, Nance Stephanie, Dang Jinjun, Xu Beisi, Ma Xiaotu, Li Yongjin, Ju Bensheng, Dong Li, Newman Scott, others
    Nature communications 2019